Vironova is a Swedish innovative company bringing new solutions to the field of sub-visible particle analysis.

Vironova offers a range of products and services which can be used in development of particles for vaccines, drug delivery and gene therapy as well as viral safety testing and material quality control.

The Vironova story

By combining expertise in electron microscopy, virology, mathematics and image analysis, Vironova has developed a unique offering of services, hardware and software products.

Application areas

Drug and gene delivery

  • Liposomal characterization
  • Morphology including lamellarity
  • Particle size distribution
  • Filled vs. empty
  • Particle shape

Vaccines

  • Viral particle morphology
  • Particle size distribution
  • Detect aggregates or debris

Material science

  • Composition distribution
  • Particle size

Biologics

  • Viral clearance

Recent updates

Open position: Software tester

We are looking for additional testers to join our development team regarding testing of two of our software products VAS and MiniTEM.
The position includes having partial responsibility for:

  • Internal testing in the development team
  • Development of the internal testing, mainly tests of the two software products (VAS and MiniTEM )
  • Quality assurance of the tests required for GAMP validation of products

Read more here (text in Swedish)

Open position: Field engineer

We are looking for a Field Engineer to join our Instruments group who will work with technical sales, installation, technical support and troubleshooting with our customers.
The service includes: customer visits and sales meetings, presenting technical demos, produce demos and technical sales and marketing materials and attend marketing events and seminars. It also includes installation, set up, testing, debugging and supporting the microscope at the customer. Education and training of customers in setting up and using the microscope is also an important part as well as managing and disclosing customers’ support needs internally.

Read more here (text in Swedish)

Reveal information that Gives Insights – New Approaches to Sub-Visible Particle Characterization

Speakers:
Dr. Josefina Nilsson, Head of EM services and Dr. Gustaf Kylberg, Product Manager MiniTEM, Vironova AB

Abstract:
A case study on how to speed up time to insight during purification and formulation development. The purity of two different Adenovirus samples were compared and analyzed. Automated image acquisition and particle classification was performed using MiniTEMTM -a compact, low voltage transmission electron microscope. High quality images and accurate quantitative data were obtained in less than 4h.

White paper: A comparative study of MiniTEM versus DLS and NTA.

This study compares the performance and the ability to detect the Adeno associated virus particles (AAV) of interest and distinguish them from contaminating proteasomes.

ProViz: A new software for easy and intuitive visualisation and analysis of electron tomograms with low signal-to-noise ratio.

Visual understanding is a key aspect when studying electron tomography data-sets, aside quantitative assessments such as registration of high-resolution structures. In a recently published article, Vironova CTO Ida-Maria Sintorn and co-authors present the free software tool ProViz (Protein Visualization) for visualisation and template matching in electron tomograms of biological samples.

Read more here.

Testimonials

Anna-Karin Maltais, CSO, </br>Eurocine Vaccines

"Being able to visualize a formulation of our nasal vaccine candidate has improved the understanding of how our adjuvant technology, Endocine™, interacts with vaccine antigens."

Anna-Karin Maltais, CSO,
Eurocine Vaccines

Vironova provides EM-services for 6 of the 10 largest pharma- and biotechnology companies.

Customers