Particle size distribution analysis
Adeno-associated virus (AAV) particles contaminated by proteasomes. Comparing MiniTEM with DLS and NTA.
MiniTEM is designed for automated characterization of sub-visible particles
MiniTEM™ is a low-voltage transmission electron microscope system. The high resolution images it acquires reveal particle morphologies that can be transformed into accurate metrics.
Automation is enabled by using a pre-configured MiniTEM software script, easily designed by dragging and dropping building blocks.
Images are automatically acquired in selected grid areas. The MiniTEM image analysis software detects and classifies particles with defined morphological characteristics. The particle classification data can then be transformed into accurate metrics.