MiniTEM - designed for sub-visible particle characterization
New regulatory requirements demand root cause analysis to understand the impact of changes during process and product development.
Nanoparticles like viruses, VLP particles and adjuvants in the 0.05-0,1 µm size range need to be quantitated, size analyzed and characterized.
MiniTEMTM transmission electron microscope is specifically designed to characterise nano-particles. As a compact low-voltage system, it runs in any laboratory setting. All you need is a standard wall socket. MiniTEMTM includes all the components you expect to find in a quality electron microscope.
Morphology analysis based on automated classification.
MiniTEM can separate particle types based on morphological appearance and provides shape and size distributions of the particles of interest.
Using direct imaging methods helps to assess the level of particle aggregation in a sample. Direct visualization allows differentiation of free versus aggregated particles.
Changes or choices at different steps during process and product development can affect particle surface properties critical for final product efficacy.
Automated to reduce manual operating time.
Automated based on structural characteristics.
Integrated detection of different macro-structures enables per particle analysis.
Visualized live and easily shared in reports.
Right where you need it
MiniTEM is a system based on the LVEM 25 desk top sized microscope from Delong Instruments a.s. The microscope uses low voltage and can be placed in standard office or GMP-compliant laboratory settings.