Full or empty analysis
AAV virus capsids and liposomal drugs are analysed by Vironova services using cryo transmission electron microscopy (CryoTEM) which allows the direct visualization of the particles in their native state. Quantitative and reliable assessment of the packaging efficiency of the particles can be performed thanks to Vironova Analyzer software (VAS).
Liposome & LNP based drugs
VAS software allows objective determination of drug content of liposomes
The VAS software measures whether the liposomes contain the drug or not. The program then presents a bar chart. The output of VAS analysis is a report with quantitative data.
Gene therapy & virus based vaccines
The VAS software in combination with cryoTEM accurately distinguishes between full and empty AAV particles
The output of VAS analysis is a report with quantitative data.