Full or empty analysis

Adenovirus and AAV analysis by cryo transmission electron microscopy (CryoTEM) allows the direct visualization of the particles in their native state, so that a quantitative and reliable assessment of the packaging of the virus particles can be performed.

Liposome & LNP based drugs

Packaging efficiency (full/empty ratio)
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VAS software allows objective determination of drug content of liposomes

The VAS software measures whether the liposomes contain the drug or not. The program then presents a bar chart. The output of VAS analysis is a report with quantitative data.

Gene therapy & virus based vaccines

Percentage full AAV capsids
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The VAS software in combination with cryoTEM accurately distinguishes between full and empty AAV particles

Cryo EM Cryo EM graph

The output of VAS analysis is a report with quantitative data.

 

Cryo EM table

Packaging

 

These analyses are part of our standard service offering. Take a closer look at VAS if you have your own acquired TEM images to analyze.

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