Vironova offers a complete GMP-certified TEM analysis package that includes both negative stain (nsTEM) analysis and cryogenic (cryoTEM) analysis, each providing powerful image datasets, quantitative data, and conclusions from the analysis.
There are a variety of nanoparticles that can be tested and analysed using TEM, at EM services we specialize in the following type of nanoparticles:
If you do not find your type of samples in the list above, please contact us. Our team of experts will suggest the type of TEM analysis suitable for your product.
We have various example reports of different types of analyses available for you to download. The reports give you a deeper insight in what to expect from hiring our electron microscopy services.
The example reports are free and easily accessed by submitting a form. Just click the button below to get to the submission page.
EM services offer a complete TEM analysis package that includes both negative stain TEM (nsTEM) and cryogenic TEM (cryoTEM). Each analysis report provides useful morphological information that is translated into quantitative and qualitative data that aids in faster and informed decision.
Please contact us through our website filling up the send us a request form or by email to info@vironova.com. One of our personnel will contact you to set up a meeting with our scientists who will explain our processes and answer your questions.
When you decide to do a service with us, we will initiate the project by preparing the required documents according to our procedures. After all the documentation is completed, we will inform you that we can receive your samples. Our delivery team will guide you through properly shipping your samples. The analysis will be performed by our senior scientists in Stockholm and the analytical report will be finalized and sent to you within 10-15 working days after the project started.
All the image analyses provided by our services are performed using our proprietary software Vironova analyzer software (VAS). VAS was specifically designed and built to answer the needs of using TEM as an analytical tool for nanoparticle characterization. Moreover, the software is FDA 21 CFR Part 11 compliant being in accordance with our EM Services GMP certified services for TEM analytics.
Your project will be performed during the reserved time slot, images and the report will be exported within 10-15 working days after the project started.
We require a minimum volume of 50 µL of sample and 2 mL of buffer, in case dilutions are needed. The sample concentration is dependent on different factors, particularly sample composition. As an example, adeno associated virus (AAV) vectors sample requires a concentration range between 1012-1013 viral particles per mL for TEM analysis. For more information on other type of samples please click here.
Since we are a GMP facility we have internal standard operating procedures that ensures a good sample traceability. After analysis and the thawing process, the remaining samples & buffers are stored at 2-8oC or at room temperature for a maximum of 30 days. To avoid cross-contamination we do not use the buffer from one project to another. For the same reason, we also do not recommend the use of the same sample vial for two different projects. Please contact us if you have a special request.
The sample submission form (SSF) is the document with the unique project number which can be traced back to the unique sample name. For this reason, it is of extreme importance that our delivery team receives the SSF together with the sample shipment. This ensures the traceability between the sample shipment and the project.
If you have any questions you would like to get answered, don’t hesitate to contact us. Answers might also be found in our learning center or in our FAQ sections on each single analysis page.
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