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On this page we have gathered important documents about our products and services in one place, to simplify the process of finding the correct information. All documents are categorized and you can filter through them by our products and services. You will also find comprehensive tutorials and user manuals explaining how our systems and software work.
We have also gathered video content created by us. Here, you can get to know Vironova at a deeper level or watch video tutorials of how to use our systems and software.
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MiniTEM offers an in-house solution that enables non-experts in electron microscopy to rapidly obtain meaningful nanoparticle characterization data.
General description and detailed specifications for Vironova MiniTEM system.
This study highlights the possibility of automated viral integrity measurements of AAV and Adenovirus particles. The analysis is performed using MiniTEM-enabled automated imaging, particle detection, classification and quantification. It provides a metric for determining the proportion of intact or broken particles in virus samples.
A metric for sample purity based on the ratio of the total area of debris to that of intact Adenovirus particles is presented in this study.
A comparative study of MiniTEM versus DLS Zetasizer Nano and NTA nanoSight NS300 performance when analyzing < 50 nm particles.
Transmission electron microscopy (TEM) can provide unique insights when characterizing viral gene delivery platforms such as those based on adeno-associated viruses (AAVs). Morphological characterization can support process development by confirming purity and status of the viral capsids.
An important discussion about gene therapy manufacturing, including the latest in manufacturing methods, analytical analysis, and key regulatory considerations.
In this case study, six different purified influenza VLP samples taken after the downstream process were analyzed. Relative quantification of influenza VLP particles with hemagglutinin spikes, as well as the amount of particles without spikes, debris and baculovirus in each sample, was calculated and presented graphically. This information can be used to confirm that critical morphological features are maintained, and impurities removed, during the manufacturing process.
General description and detailed specifications for Vironova ViroTEM system.
Objective characterization of liposomal drug delivery platforms: Using cryoTEM and designated image analysis software
Transmission electron microscopy (TEM) can provide unique insights when characterizing viral gene delivery platforms such as those based on adeno-associated viruses (AAVs). Morphological characterization can support process development by confirming purity and status of the viral capsids.
Test description
Test version
This is a guide how to remove a sample using MiniTEM 1.0.
This is a guide how to insert a sample using MiniTEM 1.0.
How to clean and care for the MiniTEM sample holder.
Cette vidéo montre comment retirer correctement le porte objet du microscope MiniTEM en utilisant l'assistant d'échange d'échantillon.
(Sample holder remove)
Cette vidéo montre comment insérer correctement le porte objet dans le microscope MiniTEM en utilisant l'assistant d'échange d'échantillon.
(Sample holder insert)
Cette vidéo montre comment nettoyer et s'occuper du porte échantillon du MiniTEM.
(Sample holder maintenance)
This video shows how to correctly remove the sample holder from the MiniTEM microscope using the wizard in VIAS 3.0 or VIAS 3.1.
This video shows how to correctly insert the sample holder into the MiniTEM microscope using the wizard in VIAS 3.0 or VIAS 3.1.
How to clean and care for the MiniTEM sample holder.
Cette vidéo montre comment retirer correctement le porte objet du microscope MiniTEM en utilisant l'assistant d'échange d'échantillon de VIAS 3.0 ou 3.1. (Sample holder remove VIAS 3.0 or 3.1)
Cette vidéo montre comment insérer correctement le porte objet dans le microscope MiniTEM en utilisant l'assistant d'échange d'échantillon de VIAS 3.0 ou 3.1. (Sample holder insert VIAS 3.0 or 3.1)
Cette vidéo montre comment nettoyer et s'occuper du porte échantillon du MiniTEM (Sample holder maintenance).
This video shows a general overview of how to create a statistical analysis tree using VIAS 3.1 or 3.0.
This video shows you how to correctly perform glow discharge of the electron microscopy grids for the MiniTEM system using a grid glow discharge unit equipped with an oil pump.
This video shows you how to correctly perform sample preparation and negative staining for grids to use in the MiniTEM system.
This video shows you how to correctly perform sample preparation in a biosafety cabinet with negative staining for grids to use in the MiniTEM system.
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