MiniTEM™ for quality analysis of phage preparations

MiniTEM™ for quality analysis of phage preparations

On January 29th Vironova will be attending The Phage Futures Congress in Washington D.C. to follow key industry trends together with peers from biotech companies and academia. Experts from regulatory bodies, pharmaceutical companies and government institutions will discuss how to actively progress clinical science and viable phage application routes to market.

Bacteriophages are a promising alternative treatment for (antimicrobial resistant) bacterial infections. A simple method to determine the stability and integrity of phage cocktails over time is needed to guarantee the success of phage treatment.

Meet Chris Bishop, Ulla Sundberg, and Vanessa Carvalho from Vironova in the dedicated poster area, in the networking break on January 29th, where we have a poster presentation to show the potential of MiniTEM™our desktop low-voltage (25 keV) transmission electron microscope. MiniTEM is used to automatically acquire images of phage cocktails of different integrities and Vironova have developed a script that detects, and provides morphological measurements of, phages particles. The direct visual information on sample content and particle morphology were key for understanding the number and intactness of the different phage particles comprising the cocktail targeting Escherichia coli

In short, at our poster session at the Phage Futures Congress, we will show that MiniTEM™ can be applied for quality analysis of phage preparations.

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