Webinar: Meaningful analytics data for quick decision making in development of viral vector-based therapies
In both early-stage and late-stage development operations of viral vector-based therapies - such as gene therapies, vaccines, or oncolytic virotherapy - access to accurate analytical data is critical. Reduction of risk and quick decision making translate into direct savings of time and money. With innovative transmission electron microscopy (TEM) technology, attributes such as viral particle size and intactness can be automatically imaged and measured.
- Visual evidence turned into quantitative data will confirm critical quality attributes of viral products
- Instant results on purity and integrity allows process adjustments within hours
Key Learning Objectives:
- TEM-based image analysis can identify and quantify the amount of detailed surface structures on viral particles
- Removal of impurities at each step of the virus purification can be monitored by using TEM-based image analysis.
- Failure in viral particle packaging and loss of integrity can be quantified by TEM-based methods.
Original send date: April 10, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
Vanessa Carvalho - Senior Scientist and Ph.D. at Vironova
Vanessa worked on membrane protein structural characterization using several electron microscopy techniques during her doctoral studies in Structural biology from TU Delft. Before earning her doctorate, Vanessa worked in different research groups mainly using protein purification and X-ray crystallography techniques. Her profound knowledge in structural biology and electron microscopy bring valuable contributions to the development of image analysis solutions and innovations at Vironova.
Gustaf Kylberg - Senior Research Scientist and Ph.D. at Vironova
Vanessa and Gustaf