New publication together with FinVector OY on the application of MiniTEM in gene therapy

Vironova has published a new article on BioProcess International today together with our friends at FinVector Vision Therapies Oy, Finland. It's a detailed explanation of how MiniTEM can be used for gene therapy applications and well worth a read. You can find it here.

Some extracts:
“TEM helps users understand what happens with viral particles when changes occur in parameters or process operations or when formulations are modified. Different biomanufacturing process conditions have different effects on particle characteristics, and images that reveal particle morphology together with quantitative analysis can provide a good understanding of and insights about the impact of such process changes.

Automated analysis from a MiniTEM system offers the advantage of removing user variability and enables analysis of a larger number of particles than possible with traditional manual methods. Thus, it is an objective analytical tool that provides statistically significant metrics.”

“By detecting particles in areas of good staining quality, a MiniTEM system produces consistent and reliable results. Hundreds of images at multiple positions of a grid can detect several thousand particles automatically in a couple of hours”.