MiniTEM is the innovation that puts the power of TEM technology in your hands
- Rapid nanoparticle characterization
- Meaningful data on particle morphology, size distribution and purity
- Easy to use and place
Developed specifically for nanoparticle characterization
- Resolution of 1 nm
- Accelerating voltage 25kV
The system can be plugged into a standard wall socket and can be placed in any standard laboratory setting – close to your process.
Images and quantitative data on nanoparticles
- Overall morphology and particle integrity
- Particle size distribution
- Particle clustering or aggregation
Automated imaging and image analysis
The automation aspect of MiniTEM provides automatic image acquisition and subsequent analysis and data presentation. Pattern recognition and machine learning capabilities enable MiniTEM to perform advanced particle characterization, classification and measurements. The results are statistically relevant thanks to the automatic acquisition and analysis of a large number of images.
(A) Waypoints are selected. (B) Images are automatically acquired in selected waypoints. (C) A large number of images are obtained. (D) Particles are detected and classified in the images. (E) Defined morphological characteristics are transformed into accurate metrics.
MiniTEM in process development
MiniTEM complements existing routine analysis methods in process development. The system offers an in-house solution that enables non-experts in electron microscopy to rapidly obtain meaningful nanoparticle characterization data. It automatically images, detects and analyzes particles. In a few hours you generate quantitative data and images of your nanoparticles that can support decision making in the optimization of your process.
A comparative study of MiniTEM versus DLS and NTA
A comparative study of MiniTEM versus DLS Zetasizer Nano and NTA NanoSight NS300 performance when analyzing < 50 nm particles.
Automated purity analysis of Adenovirus samples
A metric for sample purity based on the ratio of the total area of debris to that of intact Adenovirus particles is presented in this study.
Automated integrity analys of AAV and Adenovirus-071118
Detection of hemagglutinin spikes on influenza VLPs using automated MiniTEM analysis