Vironova Analyzer Software – quantitative and traceable nanoparticle analysis

Automated TEM image analysis with VAS gives objective data, faster

VAS is a stand alone 21 CFR part 11 compliant software for TEM based image analysis of nanoparticles. VAS semi-automates particle detection by algorithmically identifying particle characteristics based on size or shape. You can analyze many images and a large number of particles until reaching statistical significance, typically 1500 per sample. The results are graphically presented in histograms. Using VAS can save up to 6 hours per sample compared to manual approaches.

 

 

 

Objective characterization of liposomal drug delivery platforms

In cryo-transmission electron microscopy (cryoTEM) the specimen is kept at cryogenic temperatures while observed under the microscope. This allows direct visualization of native particles and analysis of their internal features.

CryoTEM combined with image analysis using VAS represents an optimized methodology for objective characterization and analysis of features such as encapsulation efficiency, level of lamellarity and thickness of the lipid bilayer of liposomal drug products.

 

 

 

Validated AAV percentage full capsid analysis

Virus particle packaging analysis with cryoTEM in combination with VAS is a patented method and the first validated method in the world for AAV percentage-full-capsid analysis. This method is recommended for batch release testing and QC of AAV-based gene therapy products.

 

 

Sample description (optional)

Analysis objective (optional)

Services

Study Proposal Form

Please fill out the following information with as much detail as you can, in order for us to provide you with an accurate quote as soon as possible.

* - Compulsory fields
What is the nature of the product
If relevant, where will the product be marketed
Should the study be performed in compliance with GLP
Should the study be performed in duplicate
Will a representative from your company be present during the testing
Process steps to be tested Model viruses Processing time Number of points for sampling If representative(s) will be present, please specify for which step(s)
Vironova Biosafety
Thank you for your interest.